Searchable abstracts of presentations at key conferences in endocrinology

ea0089c34 | Clinical – Surgery/Applied Pathology | NANETS2022

Grade Creep and the Importance of Tissue Sampling: Changes in Ki-67 and Grade in Serial Neuroendocrine Tumor Samples

Byun Suzie , M. DePietro Daniel , Ackerman Daniel , P. Gade Terence , C. Soulen Michael

Background: Neuroendocrine tumor (NET) grade, which utilizes Ki-67 expression, is a useful prognostic tool and aids in treatment decisions. However, it is not well known how these measures evolve over time. This retrospective review evaluates changes in Ki-67 and grade over time in patients with multiple NET tissue samples.Methods: 77 patients were included (44M; mean age 58±9.5 years at first sample). Primary NET sites included 46 small bowel, 21 pan...